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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: J Neuroimmune Pharmacol. 2019 Dec 10;15(3):554–563. doi: 10.1007/s11481-019-09895-6

Figure 5. Downstream effects of changes in Tspan2 gene expression.

Figure 5.

HTHU exosomes loaded with Cy5 labeled Tspan2 siRNA were applied to the apical side of the BBB, 24 hr later, HTHU-HIV microglial cells on the basolateral side were imaged or analyzed for gene expression. A) CXCL12 and CXCR4 gene expression in the presence or absence of Tspan2 siRNA in HTHU-HIV (total of n=3 experiments with 2 replicates). B) I1-13 and I1-10 gene expression in the presence or absence of Tspan2 siRNA in HTHU-HIV (total of n=3 experiments with 2 replicates).