Fig 5.
T cells are the major source of IL-13 in chronic allergic skin inflammation in mice. A, Experimental protocol for induction of chronic allergic skin inflammation in mice. B-D, Percentage (B [left]) and number (B [right]) of eGFP+ cells; numbers of eGFP+ cells (C); and mean fluorescence intensity (MFI) of eGFP expression (D) for CD4+ T cells, TCRγδ+ T cells, ILCs, basophils (Baso), and MCs in the skin of Il13egpf/+ mice subjected to chronic epicutaneous sensitization with ovalbumin (OVA). Results in B-D are representative of 2 independent experiments with 4 or 5 mice per group. Horizontal lines in B-D represent means. ∗P < .05; ∗∗P < .005; ∗∗∗P < .001. SAL, Saline.