Table 1.
Skeletal muscle metabolism of control and PTGOE mice. Glycogen, lactate, ATP, AMP, and AMP/ATP ratio were measured in the gastrocnemius muscle. Data are presented as mean ± SEM.
Fed | Fasted | |||
---|---|---|---|---|
Control | PTGOE | Control | PTGOE | |
Glycogen (mg per g tissue) | 1.4 ± 0.1 | 1.4 ± 0.1 | 1.3 ± 0.1 | 1.3 ± 0.1 |
Lactate (μmol per g tissue) | 7.7 ± 0.6 | 8.4 ± 0.3 | 7.8 ± 0.5 | 7.4 ± 0.5 |
ATP (μmol per g tissue) | 5.2 ± 0.2 | 4.9 ± 0.3 | 5.0 ± 0.1 | 4.8 ± 0.2 |
AMP (μmol per g tissue) | 0.033 ± 0.003 | 0.026 ± 0.003 | 0.073 ± 0.018* | 0.077 ± 0.014* |
AMP/ATP | 0.007 ± 0.001 | 0.005 ± 0.001 | 0.015 ± 0.004* | 0.016 ± 0.003* |
P < 0.05 between fed and fasted mice from the same genotype. n = 4–8.