Skip to main content
. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Gastroenterology. 2020 Feb 26;158(8):2236–2249.e9. doi: 10.1053/j.gastro.2020.02.034

Figure 7: MYO5B(P663L) pigs exhibit alterations in BSEP localization in hepatocytes.

Figure 7:

(A) Z-stack projections of WT liver showed well developed canaliculi with apical BSEP localization. MYO5B(P663L) presented canaliculi that appeared stunted and thickened with BSEP present below the canalicular membrane in hepatocytes. (B) MRP2 was observed on the canalicular membrane of WT and MYO5B(P663L) hepatocytes, however MYO5B(P663L) hepatocyte canaliculi appeared less developed. Scale bars=10 μm.