TABLE I.
Patient characteristics
| Variable | Value |
|---|---|
| n | 25 |
| Age (years) (mean ± SD) | 38 ±14 |
| Sex (n [percentage] male) | 19 (76%) |
| Race/ethnicity (white non-Hispanic) (n [percentage]) | 24 (96%)* |
| Time since symptom onset (years) (median [25th, 75th percentiles]) | 5 (2, 10) |
| V1 blood eosinophils (per μl) (median [25th, 75th percentiles]) | 194 (70,299) |
| V2 blood eosinophils (per μl) (median [25th, 75th percentiles]) | 158 (114,273) |
| Allergic rhinitis diagnosis or symptoms (n [percentage]) | 20 (80%) |
| VI RCAT score (mean ± SD) (n = 21) | 24.1 ± 4.3 |
| V2 RCAT score (mean ± SD) (n = 22) | 23.3 ± 4.4 |
| Asthma diagnosis (n [percentage]) | 2 (8%) |
| Treatment from V1 to V2 (n) | 12 topical steroid |
| 7 food elimination | |
| 5 both | |
| 1 other | |
| Reported use of NSAID(s) (including aspirin) (n) | 13 |
| EoE severity: | |
| Required dilations (n [percentage]) | 12 (48%) |
| Required ED visits for EoE (n [percentage]) | 13 (52%) |
| Allergic sensitivities: | |
| Trees (n [percentage]) | 17 (68%) |
| Grass (n [percentage]) | 12 (48%) |
| Ragweed/late fall pollen (n [percentage]) | 10 (40%) |
| Mold (n [percentage]) | 5 (20%) |
| Dust mite (n [percentage]) | 10 (40%) |
| Cat or dog (n [percentage]) | 9 (36%) |
| Food sensitivities: | |
| Egg (n [percentage]) | 9 (36%) |
| 2 (8%) | |
| Peanut (n [percentage]) | 6 (24%) |
| Shrimp (n [percentage]) | 5 (20%) |
| Soy (n [percentage]) | 1 (4%) |
| Wheat (n [percentage]) | 3 (12%) |
| Any above food (n [percentage]) | 13 (52%) |
| V1 PEC (per HPF) (median [25th, 75th percentiles]) | 42 (28, 68) |
| (percentage ≥ 6/HPF or ≥ 15/HPF) | 100% ≥ 6, 96% ≥ 15 |
| V2 PEC (per HPF) (median [25th, 75th percentiles]) | 12 (0, 44)† |
| (percentage ≥ 6/HPF or ≥ 15/HPF) | 56% ≥ 6, 44% ≥ 15 |
ED, emergency department; EoE, eosinophilic esophagitis; HPF, high power field; n, number of subjects; NSAID, non-steroidal anti-inflammatory drug; PEC, peak eosinophil count; RCAT, rhinitis control assessment test; V, visit.
Data are presented as mean ± SD (if data are normally distributed) or median (25th, 75th percentiles) (if data are not normally distributed).
*
One patient was white and American Indian/Alaska Native.
†
P = 0.02 versus V1.
For blood eosinophils, P = 0.96 between V2 and V1.
Allergic and food sensitivities are based on skin test.
Note: Information on NSAID use was captured as part of the information on medication but not captured in relation to study visits.