Table 4.
ELISA analysis of DNA repair proteins in peripheral blood monocytes during protocol therapy
| Subject | BRCA2 | MLH1 | ATM | KU70 | PARP1 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| W3 (%) | W6 (%) | W11 (%) | W3 (%) | W6 (%) | W11 (%) | W3 (%) | W6 (%) | W11 (%) | W3 (%) | W6 (%) | W11 (%) | W3 (%) | W6 (%) | W11 (%) | |
| A | 100 | 85 | 80 | 89 | 106 | 222 | 99 | 97 | 106 | 126 | 142 | 146 | 189 | 131 | 186 |
| B | 145 | 503 | 309 | 93 | 103 | 169 | 116 | 125 | 138 | 144 | 125 | 101 | 202 | 240 | 260 |
| C | 84 | 99 | 105 | 116 | 132 | 237 | 98 | 118 | 86 | 148 | 108 | 103 | 112 | 92 | 85 |
| D | 170 | 208 | 136 | 59 | 67 | 213 | 62 | 59 | 65 | 101 | 147 | 132 | 27 | 35 | 73 |
| E | 148 | 72 | 189 | 85 | 94 | 89 | 64 | 56 | 50 | 108 | 118 | 133 | 21 | 80 | 29 |
| F | 193 | 197 | 154 | 90 | 102 | 99 | 85 | 63 | 47 | 153 | 168 | 120 | 86 | 102 | 93 |
W = week; each measurement reported as the mean of two readings and expressed as a percentage of the baseline value (from peripheral monocytes prior to protocol therapy). Measurements representing ≥40% increase or decrease from baseline are italicized and in bold type.