Table 1.
Various definitions of cognitive impairment that is not dementia
| Term | BSF11 | CDR/QD34 | AAMI24 | AACD31 | CIND41 | Petersen MCI39 | Winblad MCI12 | NIA-AA43 | mNCD1 |
|---|---|---|---|---|---|---|---|---|---|
| Cognitive complaint | – | – | Self- or carer- complaint about memory | Self- or carer- complaint about cognition | – | Self-complaint about memory | Self- or carer- complaint about cognition | Self- or carer- complaint about cognition | Self- or carer- complaint about cognition |
| Psychometric impairment | – | – | 1 s.d. below healthy young adults | 1 s.d. below age-matched sample | Battery of neuro-psychological tests | 1.5 s.d. below age- and edu- matched sample | No cut-off specified. | Typically 1–1.5 s.d. below age- and edu-matched sample | Modest impairment; typically 1–2 s.d. below age- and edu- matched sample |
| ADL | – | Slight or mild change | – | – | – | Normal | Minimal impairment in complex instrumental ADL | Mild change, but still independently functioning | Independent, but possibly with greater effort or strategies |
| Dementia | No | No | No | No | No | No | No | No | No |
| Notes | Mild dementia may have CDR = 0.5 | At least 6 months duration | Does not exclude non-dementia causes | AKA Mayo criteria | AKA Revised Mayo criteria or revised Petersen criteria | Biomarker criteria not presented here |
AACD, aging-associated cognitive decline; AAMI, aging-associated memory impairment; ADL, activities of daily living; AKA, also known as; BSF, benign senescent forgetfulness; CDR, Clinical Dementia Rating scale; CIND, cognitive impairment not dementia; edu, education; MCI, mild cognitive impairment; mNCD, mild neurocognitive disorder; NIA-AA, National Institute on Aging and the Alzheimer's Association; QD, questionable dementia.