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. 2020 May 7;39:101008. doi: 10.1016/j.molmet.2020.101008

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© 2020 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Gain and loss of GIPR signaling impact hematopoiesis. Bone marrow, peripheral blood, and splenic cells were assessed to investigate the role of the GIPR in the control of hematopoiesis in different stress situations. HFD: high-fat diet; RCD: regular chow diet; BMT: bone marrow transplant; 5-FU: 5-fluorouracil; LPS: Lipopolysaccharide; Pam3CSK4 = Pam3CysSerLys4; GIP: glucose-dependent insulinotropic polypeptide; LK: Lin-cKit + Sca1-; MPP: multipotent progenitor; CLP: common lymphoid progenitor; CMP: common myeloid progenitor; GMP: granulocyte-monocyte progenitor.