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. 2020 May 25;15(3):261–278. doi: 10.1007/s11523-020-00717-x
Non-coding RNAs (especially long non-coding RNAs and microRNAs) have important roles as oncogenic and tumour suppressor molecules.
Long non-coding RNAs and microRNAs are attracting increasing interest as therapeutic targets after they have been used widely as biomarkers in the past.
One bottle neck is tissue- and cell type-specific delivery and targeting of deregulated non-coding RNAs as well as reducing off-target effects especially innate immune responses.