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. 2020 Jun 9;10:9329. doi: 10.1038/s41598-020-66319-9

Table 2.

PD cohort Metabolic Syndrome components.

iPD LRRK2-PD GBA-PD significance
# 104 40 70
HDL (mg/Dl) 56.20 (16.24) 62.02 (19.36) 54.24 (16.35) 0.073
Triglycerides (mg/Dl) 117.24 (57.96) 158.10 (100.48) @ 130.90 (60.60) 0.015*
HbA1c (%) 5.65 (0.54) 5.82 (0.51) 5.61 (0.59) 0.108
BMI (kg/m2) 25.58 (3.08) 25.77 (3.96) 26.03 (4.16) 0.725
Hypo-HDL (%) 20.00% 7.50% 20.80% 0.160
Hypertriglyceridemia (%) 41.90% 52.50% 38.90% 0.364
Prediabetes (%) 34.30% 65.00%@ 43.10% 0.004*
Hypertension (%) 75.20% 80.00% 79.20% 0.754
Obesity (BMI > 30) (%) 9.50% 15.00% 19.40% 0.167

iPD – idiopathic Parkinson’s Disease, HDL- High Density Lipoprotein, HbA1c – Hemoglobin A1C, BMI- Body Mass Index. *Significant after correcting for multiple comparisons with Bonferroni adjustment.

@Differences between LRRK2-PD and GBA-PD, iPD.