Table 5.
Non-manifesting carriers’ Metabolic Syndrome components.
| Control | LRRK2-NMC | GBA-NMC | Significance | |
|---|---|---|---|---|
| # | 196 | 55 | 97 | |
| HDL (mg/Dl) | 56.45 (15.76) | 56.44 (14.47) | 57.84 (17.16) | 0.694 |
| Triglycerides (mg/Dl) | 136.89 (75.66) | 146.36 (105.63)@ | 142.00 (75.01) | 0.014* |
| HbA1c (%) | 5.49 (0.48) | 5.45 (0.43) | 5.44 (0.44) | 0.683 |
| BMI (kg/m2) | 26.36 (4.78) | 26.15 (4.26) | 26.66 (4.69) | 0.785 |
| Hypo-HDL (%) | 18.97% | 23.63% | 24.21% | 0.525 |
| Hypertriglyceridemia (%) | 43.58% | 56.36% | 49.47% | 0.619 |
| Prediabetes (%) | 30.25% | 21.81% | 25.26% | 0.393 |
| Hypertension (%) | 65.12% | 58.18% | 58.90% | 0.469 |
| Obesity (BMI > 30) (%) | 20.51% | 14.54% | 27.36% | 0.163 |
NMC- Non-Manifesting Carriers, HDL- High Density Lipoprotein, HbA1c – Hemoglobin A1C, BMI- Body Mass Index. *Significant after correcting for multiple comparisons with Bonferroni adjustment.
@Differences between LRRK2-NMC and GBA-NMC, control.