Table 6.
Linear regression Models for metabolic factors in unaffected carriers. B(95%CI) and p values are presented for measures found significant in the model.
| Number of metabolic factors | Prediabetes | Hypertension | Hypertriglyceridemia | Low HDL | Obesity | |
|---|---|---|---|---|---|---|
| Model | F = 7.137; p < 0.001 | F = 5.857; p < 0.0001 | F = 0.481; p < 0.001 | F = 7.030; p < 0.0001 | F = 0.619; p = 0.781 | F = 1.148; p = 0.329 |
| Genotype | ||||||
| Sex | −0.459(−0.745–0.173); 0.002 | −0.095(−0.194–0.003); 0.058 | −0.171(−0.279–0.064); 0.002 | −0.140(−0.248–0.032); 0.002 | ||
| Age | 0.048(0.033–0.063); 0.0001 | 0.015(0.010–0.020); 0.0001 | 0.014(0.008–0.019); 0.0001 | 0.016(0.011–0.022); 0.0001 | ||
| Probability | ||||||
| RBDQ | ||||||
| UPDRS-III | −0.042(−0.077–0.007); 0.018 | |||||
| MOCA | −0.017(−0.035–0.001); 0.061 | |||||
| UPSIT | ||||||
| NMSQ |
RBDQ- REM sleep Behavior Disorder Questionnaire, UPDRS- Unified Parkinson’s Disease Rating Scale part III, MoCA- Montreal Cognitive Assessment, UPSIT- University of Pennsylvania Smell Identification Test, NMSQ- Non-Motor Symptoms questionnaire.