Table 2.
Anticancer activities of compounds 7 and 14a.
| compound | HCT116 (µM) | SW620 (µM) |
|---|---|---|
| 7a | >20 | >20 |
| 7b | 2.1 ± 0.2 | 1.4 ± 0.2 |
| 7c | >20 | 18.7 ± 6.0 |
| 7d | 1.2 ± 0.1 | 5.3 ± 1.2 |
| 7e | >20 | >20 |
| 7 f | 2.7 ± 0.7 | 3.8 ± 0.6 |
| 7 g | 1.8 ± 0.2 | 1.6 ± 0.3 |
| 7 h | 1.3 ± 0.4 | 1.8 ± 0.3 |
| 7i | >20 | >20 |
| 7j | >20 | >20 |
| 7k | 17.2 ± 5.1 | 14.5 ± 3.7 |
| 7 l | 2.9 ± 0.8 | 1.4 ± 0.5 |
| 7 m | >20 | >20 |
| 7n | >20 | >20 |
| 7o | 3.4 ± 1.0 | 2.1 ± 0.9 |
| 7p | >20 | >20 |
| 7q | >20 | >20 |
| 7r | >20 | >20 |
| 7 s | 8.5 ± 1.0 | 11.3 ± 3.3 |
| 14a | >20 | >20 |
| 14b | >20 | >20 |
| 14c | >20 | >20 |
| 14d | >20 | >20 |
| 14e | >20 | >20 |
| 14 f | >20 | >20 |
| 14 g | >20 | >20 |
| 14 h | >20 | >20 |
| 14i | >20 | >20 |
| 14j | >20 | >20 |
| Paclitaxel | 0.14 ± 0.05 | - |
aAll MTT assays were repeated three times by using six samples per assay.