Table 2.
Thermodynamic parameters of CxD7L2 protein by ITC.
| Ligand | Binding | Stoichiometry | ΔH, cal/mol ± SE | TΔS, cal/mol/deg | KD, nM |
|---|---|---|---|---|---|
| Serotonin | Yes | 1.37 | −1.63E4 ± 171.2 | −16.50 | 7.46 |
| Histamine | Yes | 0.97 | −1.31E4 ± 579.4 | −14.00 | 383.14 |
| Epinephrine | Yes | 0.94 | −5.79E4 ± 513.8 | 11.30 | 226.24 |
| LTB4 | No | N/A | N/A | N/A | N/A |
| LTC4 | Yes | 1.07 | −2.24E4 ± 621.2 | −42.80 | 151.75 |
| LTD4 | Yes | 0.98 | −1.53E4 ± 812.7 | −19.40 | 156.49 |
| LTE4 | Yes | 1.07 | −1.62E4 ± 561.8 | −22.40 | 158.73 |
| Arachidonic acid | Yes | 1.29 | −6.66E3 ± 578.4 | −5.33 | 1083.42 |
| U-46619 | Yes | 0.99 | −6.06E3 ± 474.4 | 7.58 | 934.58 |
| 5′-ATP | No | N/A | N/A | N/A | N/A |
| 5′-ADP | No | N/A | N/A | N/A | N/A |