Table 2.
Colonoscopy outcomes: combined strategy versus FIT-only strategy.
| Combined strategy (n/N (%)) | FIT-only strategy (n/N (%)) | p Valuea | |
|---|---|---|---|
| Detection rate (%)b | |||
| CRC | 14/216 (6.5%) | 14/200 (7.0%) | 0.99 |
| Advanced adenoma | 103/216 (47.7%) | 102/200 (51.0%) | 0.56 |
| Advanced neoplasia | 117/216 (54.2%) | 116/200 (58.0%) | 0.49 |
| Non-advanced lesions | |||
| Non-advanced adenoma | 49/216 (22.4%) | 42/200 (21%) | 0.77 |
| SSL+others | 21/216 (9.7%) | 18/200 (9.0%) | 0.93 |
| No lesions | 29/216 (13.4%) | 24/200 (12.0%) | 0.77 |
| Positive predictive value (%)c | |||
| CRC | 14/359 (4% (2–6%)) | 14/234 (6% (3–10%)) | 0.33 |
| Advanced adenoma | 103/359 (29% (24–34%)) | 102/234 (44% (37–50%)) | <0.01 |
| Advanced neoplasia | 117/359 (33% (28–38%) | 116/234 (50% (43–56%)) | <0.01 |
CRC colorectal cancer, SSL sessile serrated lesion.
ap Values were calculated using the Chi-square test.
bDetection rates were defined as the most advanced lesion per participant relative to all colonoscopies performed.
cPositive predictive value was defined as the number of participants with CRC, advanced adenoma or advanced neoplasia relative to the number of positive tests.