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. 2020 Jun 9;10:9313. doi: 10.1038/s41598-020-66285-2

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(A) Radiochemical yield for increasing amounts of DOTA-scFvD2B, incubated at 37 °C for 1 and 2 h. (B) Size-exclusion HPLC radiochromatograms of ¹⁷⁷Lu-scFvD2B obtained with a molar activity of 18 MBq/nmol without dilution (black line) and after 24 and 192 h dilution in 0.1 M phosphate buffer at pH 7.0 (red and blue lines respectively).