Table 1.
Distribution of 130 patients with oropharyngeal carcinomas according to socio-demographic and clinical characteristics.
| Total patients | HPV-driven cancers | CMH testa | ||
|---|---|---|---|---|
| n | n | (%) | ||
| Gender | ||||
| Female | 35 | 18 | (51.4) | |
| Male | 95 | 24 | (25.3) | p = 0.005 |
| Age (years) | ||||
| <65 | 68 | 21 | (30.9) | |
| ≥65 | 62 | 21 | (33.9) | p = 0.717 |
| Year of diagnosis | ||||
| 2000–2006 | 36 | 6 | (16.7) | |
| 2007–2012 | 42 | 12 | (28.6) | |
| 2013–2018 | 52 | 24 | (46.2) | p < 0.001 |
| Cancer subsite | ||||
| Base of tongue | 28 | 11 | (39.3) | |
| Tonsil | 84 | 30 | (35.7) | |
| Other | 18 | 1 | (5.6) | p = 0.021c |
| TNM stage (7th ed.) | ||||
| I-II | 13 | 3 | (23.1) | |
| III | 23 | 11 | (47.8) | |
| IV | 94 | 28 | (29.8) | p = 0.995 |
| TNM stage (8th ed.) | ||||
| I-II | 38 | 27 | (71.1) | |
| III | 27 | 15 | (55.6) | |
| IV | 65 | 0 | (0.0) | p < 0.001 |
| Grading | ||||
| Well differentiated | 10 | 2 | (20.0) | |
| Moderately differentiated | 53 | 13 | (24.5) | |
| Poorly differentiated | 55 | 20 | (36.4) | p = 0.143 |
| Unknown | 12 | 6 | (50.0) | |
| Tobacco smoking | ||||
| Never | 26 | 18 | (69.2) | |
| Former | 30 | 10 | (33.3) | |
| Current | 74 | 14 | (18.9) | p < 0.001c |
| Alcohol drinkingb | ||||
| Never | 54 | 30 | (55.6) | |
| Former | 13 | 1 | (7.7) | |
| Current | 61 | 10 | (16.4) | p < 0.001c |
aCochran-Mantel-Haenszel test; bTwo patients did not report drinking habits; cFisher exact test.