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. 2020 Jun 9;10:9257. doi: 10.1038/s41598-020-66138-y

Table 4.

Crude and adjusted ORs for the associations between serum TBA as a categorical variable and SGA infants.

Parameter Pregnant women (n) SGA (n) Crude OR (95% CI) Adjusted OR (95% CI) a Adjusted OR (95% CI) b
Serum TBA levels (μmol/L)
    <2.0 3196 193 1.00 1.00 1.00
    2.0–3.9 4580 278 1.01 (0.83, 1.22) 1.02 (0.85, 1.24) 0.99 (0.82, 1.21)
    4.0–5.9 2075 160 1.30 (1.05, 1.62)* 1.31 (1.06, 1.63)* 1.22 (0.97, 1.53)
    6.0–7.9 835 108 2.31 (1.80, 2.97)** 2.32 (1.81, 2.97)** 1.99 (1.53, 2.58)**
    8.0–9.9 434 83 3.68 (2.78, 4.87)** 3.64 (2.75, 4.82)** 2.91 (2.16, 3.93)**
    10.0–39.9 563 138 5.05 (3.97, 6.43)** 5.10 (4.00, 6.49)** 4.29 (3.33, 5.54)**
    ≥40.0 128 50 9.98 (6.80, 14.64)** 9.90 (6.74, 14.55)** 9.01 (5.99, 13.53)**

Abbreviation: TBA, total bile acid; SGA, small for gestational age; OR, odds ratio.

aAdjustment for gestational hypertension.

bAdjustment for maternal age, pre-pregnancy BMI, maternal education, parity, gestational diabetes mellitus, gestational hypertension and preeclampsia.

**P < 0.01 as compared with < 2.0 μmol/L group.