Fig. 5. Effect of forced FKBP51s expression on monocytes’ co-stimulation markers.

a QPCR measure of ARG1 and MSR1 transcript levels in RNA extracted by healthy donors’ macrophages transfected with FKBP51s or empty vector (EV) as control. Values of FKBP51s- overexpressing monocytes were expressed as fold change, using the EV-monocyte value as reference sample (=1). b Graphic representation of flow cytometric values of expression of CD80, PD-L1, IL-10 and HLA-DR, in EV- or FKBP51s macrophages, from four healthy donors, and c representative flow cytometry histograms. d Western blot assay of pSTAT3 levels in FKBP51s macrophages.