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Patient characteristics.
| Responders (11) | Non-responders (11) | |
|---|---|---|
| Age in years—median (range) | 69 (41–84) | 71 (31–82) |
| Sex (M:F) | 1:1.75 | 1.25:1 |
| Locally/advanced/inoperable | 27.3% (3) | 27.3% (3) |
| M1a | 54.5% (6) | 27.3% (3) |
| M1b | 18.2% (2) | 0% (0) |
| M1c | 0% (0) | 45.5% (5) |
| M1d | 0% (0) | 0% (0) |
| BRAF V600 mut | 0% (0) | 27.3% (3) |
| NRAS mut | 18.2% (2) | 36.4% (4) |
| Previous BRAFi + MEKi | 0% (0) | 27.3% (3) |
| PFS months—median (range) | 17.3 (4.2–30.3) | 3.1 (0.5–5.3) |
