Table 5.

Multivariate Logistic Regression Analysis of Left Ventricular Geometry with Vascular Ageing Parameters

	LVH		LVCG		Left Ventricular Geometry
					Concentric Remodelling (n =741)		Eccentric LVH (n =537)		Concentric LVH (n =238)
	OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P
Model 1
Arteriosclerosis	1.417(1.184–1.696)	<0.001*	1.332(1.134–1.564)	<0.001*	1.359(1.131–1.634)	0.001*	1.477(1.193–1.829)	<0.001*	1.880(1.378–2.563)	<0.001*
Peripheral atherosclerosis	1.345(1.058–1.709)	0.015*	1.505(1.214–1.865)	<0.001*	1.524(1.179–1.968)	0.001*	1.376(1.020–1.855)	0.036*	2.016(1.392–2.920)	<0.001*
Micro-albuminuria	1.744(1.444–2.105)	<0.001*	1.177(1.004–1.379)	0.044*	1.261(1.051–1.512)	0.013*	1.968(1.590–2.437)	<0.001*	1.888(1.397–2.550)	<0.001*
Decreased eGFR	0.869(0.707–1.068)	0.181	0.849(0.699–1.033)	0.102	1.206(0.960–1.516)	0.107*	0.885(0.691–1.132)	0.330	1.007(0.712–1.423)	0.970
cIMT>0.9 or plaque	0.929(0.777–1.111)	0.419	1.017(0.864–1.197)	0.839	1.050(0.869–1.267)	0.615*	0.947(0.765–1.173)	0.617	0.889(0.661–1.196)	0.436
Model 2
Arteriosclerosis	1.343(1.112–1.622)	0.002*	1.290(1.090–1.528)	0.003*	1.320(1.088–1.602)	0.005*	1.406(1.125–1.759)	0.003*	1.731(1.253–2.393)	0.001*
Peripheral atherosclerosis	1.376(1.070–1.770)	0.013*	1.526(1.219–1.910)	<0.001*	1.583(1.211–2.069)	0.001*	1.440(1.054–1.968)	0.022*	2.019(1.370–2.976)	<0.001*
Micro-albuminuria	1.829(1.525–2.194)	<0.001*	1.150(0.979–1.352)	0.089	1.229(1.022–1.479)	0.025*	1.969(1.585–2.446)	<0.001*	1.888(1.390–2.564)	<0.001*
Model 3
Arteriosclerosis	1.282(1.046–1.572)	0.017*	1.301(1.085–1.561)	0.005*	1.347(1.094–1.659)	0.005*	1.369(1.075–1.742)	0.011*	1.615(1.143–2.282)	0.007*
Peripheral atherosclerosis	1.236(0.954–1.602)	0.109	1.459(1.163–1.831)	0.001*	1.523(1.164–1.991)	0.002*	1.307(0.951–1.797)	0.099	1.681(1.127–2.506)	0.011*
Micro-albuminuria	1.690(1.398–2.043)	<0.001*	1.170(0.991–1.382)	0.064	1.243(1.028–1.504)	0.025*	1.812(1.446–2.270)	<0.001*	1.783(1.299–2.447)	<0.001*
Model 4
Arteriosclerosis	1.291(1.044–1.598)	0.019*	1.271(1.051–1.537)	0.013*	1.329(1.069–1.651)	0.010*	1.393(1.083–1.791)	0.010*	1.577(1.104–2.254)	0.012*
Peripheral atherosclerosis	1.276(0.973–1.673)	0.078	1.515(1.197–1.918)	0.001*	1.603(1.215–2.116)	0.001*	1.346(0.967–1.874)	0.079	1.704(1.129–2.573)	0.011*
Micro-albuminuria	1.695(1.401–2.051)	<0.001*	1.172(0.990–1.386)	0.065	1.257(1.038–1.522)	0.019*	1.815(1.447–2.277)	<0.001*	1.812(1.320–2.489)	<0.001*

Notes: Multivariate logistic regressions were conducted to detect the regression coefficients and odds ratios (ORs) of vascular ageing parameters in LVH/LVCG, and 3 abnormal LV geometry. Model 1: adjusted for age and gender, respectively. Model 2: adjusted for age and gender, then vascular ageing parameters were incorporated in the model. Model 3: adjusted for conventional cardiovascular risk factors and diseases and treatments, respectively. Model 4: adjusted for conventional cardiovascular risk factors and diseases and treatments, then vascular ageing parameters were incorporated in the model. *P<0.05.

Abbreviations: LVH, left ventricular hypertrophy; LVCG, left ventricular concentric geometry, eGFR, estimated glomerular filtration rate; cIMT, carotid artery intima-media thickness.