Table 1.
Detected mutations and their implications for binding sites in the S portion of the SARS‐CoV‐2
| AA a position in the S gene | Bat‐CoV b | SARS‐CoV‐2 c | Mutation involved in binding sites |
|---|---|---|---|
| 32 | S | F | X |
| 50 | L | S | |
| 76 | I | T | |
| 218 | P | Q | X |
| 324 | D | E | |
| 346 | T | R | |
| 372 | T | A | |
| 403 | T | R | |
| 439 | K | N | |
| 440 | H | N | |
| 441 | I | L | |
| 443 | A | S | |
| 445 | E | V | |
| 449 | F | Y | |
| 459 | A | S | |
| 478 | K | T | |
| 483 | Q | V | |
| 484 | T | E | |
| 486 | L | F | |
| 490 | Y | F | |
| 493 | Y | Q | |
| 494 | R | S | |
| 498 | Y | Q | |
| 501 | D | N | |
| 505 | H | Y | |
| 519 | N | H | |
| 604 | A | T | |
| 680 | S | SPRRA d | X |
| 1121 | S | N | |
| 1224 | I | V |
Abbreviation: SARS‐CoV‐2, severe acute respiratory syndrome coronavirus 2.
a
AA, amino acid position.
b
AA in the S portion of the genome of the bat coronavirus strain RaTg13.
c
AA change in the SARS‐CoV‐2 genome.
d
SPRRA insertion in the SARS‐CoV‐2 genome.