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. 2020 Jun 3;11:917. doi: 10.3389/fimmu.2020.00917

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Copyright © 2020 Albazli, Kaminski and Howard.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Quantitative myasthenia gravis (QMG) score change from baseline over 12 weeks for eculizumab vs. placebo. Using patient data at the end of both period visits, overall change in mean QMG total score was significantly different between eculizumab and placebo (−7.92 vs. −3.67; paired t-test p = 0.0144). Using patient data at all visits, overall change in mean QMG total score was significantly different between eculizumab and placebo (−6.43 vs. −3.18; repeated-measures mixed model p < 0.0001). Modified from Howard et al. (48).