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. 2020 Jun 3;7:84. doi: 10.3389/fnut.2020.00084

Table 1.

Characteristics of the studies that combined calorie restricted diets with polyphenols.

References, Country Length months Age range (mean/SD) % of females N (CRD/ CRD-PP) BMI by groups (mean/SD) Health status CRD Suppl CRD-PP Suppl form: polyphenol type and dosage per day Diet protocol
Ibero-Baraibar et al. (32) Spain 1 50-80
(57.3/5.3)
54% 47
(24/23)
CRD: 30.3/1.9
CRD-PP:
30.7/2.5
Healthy No Suppl Cocoa extract:
Flavanols 645 mg
LCD
15%*
Mielgo-Ayuso et al. (33) Spain 3 19-49 100% 83
(40/43)
CRD: 34.3/3.0
CRD-PP:
33.7/2.6
Healthy Lactose
Capsule
Capsule: EGCG
300 mg
LCD 600 Kcal*
Silver et al. (34) US 3 21-50
(38.7/8.2)
75% 68 (23/23 Gf/22 Gfj) CRD: 35.7/3.5
CRD-PP (Gf):
36.3/3.1
CRD-PP (Gfj):
35.2/3.1
27% Metabolic
Syndrome
Water Gf: Naringin 81 mg
Gfj: Naringin 119 mg
LCD 12.5%*
Diepvens et al. (35) Netherlands 3 19-57
(41.2)
100% 46
(23/23)
CRD: 27.6/1.8
CRD-PP:
27.7/1.8
Healthy Md Capsule GT-Capsule:
Catechins
1125 mg (225 mg CF)
LCD

BMI, body mass index (kg/m2); CF, caffeine; CRD, calorie restriction diet intervention group; CRD-PP, calorie restriction plus polyphenol intervention groups; EGCG, epigallocatechin-gallate; Gf, grapefruit; Gfj, grapefruit juice; GT, green tea; Kcal, kilo calories; LCD, low calorie diet; Md, maltodextrin; N, number of participants in both groups and (by groups); SD, standard deviation; Suppl, supplementation; US, United States.

*

Calorie deficit per day.