TABLE 2.
EAHE group (n = 20) | Placebo group (n = 21) | ||||
Variables | Value | Intragroup p-value | Value | Intragroup p-value | Intergroup p-value |
NPI | |||||
Baseline | 4.21 ± 6.62 | – | 3 ± 5.2 | – | 0.696 |
Week 13 | 0 ± 0 | 0.306 | 1.33 ± 1.53 | 0.812 | 0.259 |
Week 25 | 1.5 ± 2.12 | 0.439 | 1.33 ± 2.31 | 0.087 | 0.989 |
Week 49 | 0.67 ± 1.15 | 0.077 | 2.25 ± 3.3 | 0.163 | 0.129 |
CASI | |||||
Baseline | 71.75 ± 17.12 | – | 73.52 ± 14.51 | – | 0.804 |
Week 13 | 72.74 ± 15.83 | 0.246 | 70.71 ± 19.3 | 0.13 | 0.881 |
Week 25 | 73.8 ± 17.15 | 0.313 | 69.62 ± 16.07 | 0.043* | 0.368 |
Week 49 | 75.35 ± 15.86 | 0.058 | 69.67 ± 16.62 | 0.064 | 0.315 |
MMSE | |||||
Baseline | 21.75 ± 6.1 | – | 21.33 ± 5.74 | – | 0.629 |
Week 13 | 22.58 ± 5.6 | 0.065 | 20.95 ± 6.47 | 0.616 | 0.4 |
Week 25 | 22.55 ± 6.24 | 0.23 | 21.05 ± 5.5 | 0.686 | 0.353 |
Week 49 | 23.2 ± 5.92 | 0.035* | 20.67 ± 6.17 | 0.661 | 0.261 |
IADL | |||||
Baseline | 6.35 ± 2.81 | – | 5.71 ± 2.65 | – | 0.25 |
Week 13 | 6.37 ± 2.31 | 1 | 6 ± 2.07 | 0.484 | 0.423 |
Week 25 | 6.45 ± 2.58 | 0.705 | 5.57 ± 2.29 | 0.634 | 0.11 |
Week 49 | 6.7 ± 2.47 | 0.157 | 5 ± 2.7 | 0.075 | 0.012* |
Values are given as mean ± SD. NPI = Neuropsychiatric Inventory; CASI = Cognitive Abilities Screening Instrument; MMSE = Mini mental state Examination; IADL = Instrumental Activities of Daily Living. ∗p < 0.05.