Figure 2.

Clinical Examination Data following Intrastromal Injection

(A–C) Inflammatory scores (A), intraocular pressure (IOP) (B), and central corneal thickness (CCT) (C) following corneal instrastromal injection with either 50 μL of saline (n = 6), AAV-IDUA at 1e9 vg (n = 8), or AAV-IDUA at 1e10 vg (n = 8) using a 31G needle. Mild inflammation was observed in all eyes following injection, which resolved by day 7, was not significantly different between groups, and did not recur during the 6-month study period. CCT and IOP also did not differ between groups. Data are presented as the Mean ± SD.