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. 2020 Jun 6;6(6):e04055. doi: 10.1016/j.heliyon.2020.e04055

Table 1.

Some benzimidazole-based drugs along with their trade names, classified according to their status by the World Health Organisation (WHO), biological target for the initial therapeutic indication, and cost per single dose.

Mebendazole Albendazole Triclabendazole Omeprazole Bendamustine
Trade Name Vermox® Albenza® Egaten® Losec® Treanda®
WHO Ess. Med. Yes Yes Yes Yes Yes
Target Parasitic worms Parasitic worms Parasitic worms PPI Leukemia, lymphoma, myeloma [7].
Anticancer Potential CBCIs, kinase inh [8]. (colon, lung, adrenocortical, breast cancer) [9] Modulation of oxidative stress, induction of DNA damage [10]. (colorectal, hepatoc. carcinoma) Abcg2 inh [11]. FASN thioesterase activity inh. [12], colon cancer [13].
Cost (USD)/Dose 0.04–0.004 0.06 0.01–0.06 0.06