Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jun 5;4(11):2477–2488. doi: 10.1182/bloodadvances.2019001364

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by The American Society of Hematology

PMC Copyright notice

Figure 4. — Characterization of MF HSPCs and serial repopulation analysis. (A) Representative flow cytometry plots of the human stem (hCD34⁺hCD38⁻) and progenitor (hCD34⁺hCD38⁺) cell fraction out of total hCD45⁺ cells from 3 MISTRG mice transplanted with 3 different samples (10, 11, and 13). (B) Workflow for serial transplantation of purified hCD45⁺ cells from primary into secondary MISTRG mice. (C, left) Flow cytometry plots of primary and secondary MISTRG mice from sample 13, 9.7 weeks (primary MISTRG) and 17.9 weeks (secondary MISTRG) post-transplantation, respectively. (C, right) Total human engraftment in the BM, PB, and SPL of secondary MISTRG recipients. Each dot represents an individual mouse; each color represents an individual patient. (D) Distribution of human B-lymphoid and myeloid lineages. Results are expressed as mean ± standard deviation.