Fig. 1.

Compound screening workflow from a customized Selleckchem® drug library. (A) Distribution of the whole compound library (top pie chart) and the primarily selected compounds (bottom pie chart) per reported functional pathway. (B) Stepwise schematic of compound screening and hit selection based on phenotypic observation and motility recording of compound-treated S. mansoni schistosomulae and adult stages (C) Compound analysis in Spotfire: Plot of tPSA vs cLogP of compounds screened from Selleckchem® library.