Table 3.

DG Binding free energy of the NSP10/NSP16 methyltransferase (PDB: 6w61) and main protease (PDB: 6lu7) with selected compounds.

SN	Compounds (NSP10/NSP16 methyltransferase)	DG binding free energy	Compounds (Main protease)	DG binding free energy
1	Oxytetracycline dihydrate	−52.55	Penciclovir	−42.90
2	TYZEKA (Telbivudine)	−51.56	Cyclocytidine hydrochloride	−33.61
3	2-deoxy-D-glucose	−41.18	Meropenem	−30.36
4	Daphnetin	−38.47	Trifluridine	−30.18
5	Methylgallate	−37.61	Adonitol	−29.13