Table 3.
Non-invasive assessment data obtained at baseline and sustained virologic response 12 from patients stratified according to the fibrosis grade
| Parameter | P value | ||||
| Baseline (Total n = 80) | F0-1 (n = 29) | F2 (n = 20) | F3 (n = 5) | F4 (n = 26) | |
| LSM (kPa) | 5.9 ± 0.6 | 7.8 ± 0.5 | 10.8 ± 1.2 | 20.6 ± 7.7 | < 0.001b |
| FIB-4 score | 1.7 ± 1.4 | 1.4 ± 0.7 | 1.8 ± 0.4 | 2.3 ± 1.5 | 0.108 |
| PAPAS index | 2.1 ± 0.4 | 2.2 ± 0.6 | 2.3 ± 0.3 | 2.3 ± 0.5 | 0.303 |
| Serum M2BPGi (ng/mL) | 4.5 ± 2.2 | 5.3 ± 2.8 | 9.4 ± 4 | 14.5 ± 6.7 | 0.001b |
| SVR 12 (Total n = 80) | F0-1 (n = 35) | F2 (n = 23) | F3 (n = 6) | F4 (n = 16) | |
| LSM (kPa) | 5.8 ± 1.2 | 7.6 ± 0.6 | 9.9 ± 0.8 | 15 ± 2.3 | < 0.001b |
| FIB-4 score | 1.1 ± 0.5 | 1.5 ± 1 | 1.3 ± 0.6 | 1.6 ± 0.5 | 0.075 |
| PAPAS index | 2 ± 0.3 | 2.1 ± 0.3 | 2.1 ± 0.3 | 2.3 ± 0.3 | 0.069 |
| Serum M2BPGi (ng/mL) | 3.4 ± 1.6 | 4.9 ± 2.1 | 12.7 ± 5.1 | 13.3 ± 5.2 | 0.001b |
b
P < 0.01. The values are expressed as mean ± SD. SVR: Sustained virologic response; LSM: Liver stiffness measurement; M2BPGi: Mac-2 binding protein glycosylation isomer.