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. 2020 Apr 13;7(11):1903630. doi: 10.1002/advs.201903630

Figure 6.

Figure 6

A schematic depicting the interplay of UCA1 with EZH2 to mediate As‐induced G2/M phase arrest. Interaction between UCA1 and EZH2 protein resulted in latter phosphorylation and ubiquitylation mediated by CDK1, consequently activating NFATc2 to antagonize the As‐blocked cell cycle.