Figure. Adjusted Incidence Rates for Major Cardiovascular Disease Events per 1000 Person-Years in a Study of the Association of Migraine With Aura With Incident Cardiovascular Disease in Women.

The vertical line indicates the adjusted incidence rate for migraine with aura. Values to the left of the vertical line indicate lower and values to the right indicate higher adjusted incident rates of major cardiovascular disease compared with the incidence rate of migraine with aura. Adjusted for all factors listed as well as age (5-year groups), alcohol use, exercise, hypertensive treatment, ever use of hormones, and premenopausal status. Because 2 different approaches were used for categorizing covariates in the multivariable models, the estimated adjusted incidence rates differ slightly in the Figure (in which some covariates were categorized as polychotomous) and in Table 2 (in which all covariates were categorized as dichotomous).

^aP value was calculated using a χ² test. HDL indicates high-density lipoprotein; BP, blood pressure; MI, myocardial infarction.