Table 2.
The sensitivity and specificity of a range of diagnostic cut-off reciprocal titres of IFA IgM and IgG using Bayesian latent class models for the true diagnosis of murine typhus in admission samples
| Reciprocal IFA titre | IgM cut-off |
IgG cut-off |
||
|---|---|---|---|---|
| Sensitivity (%) (95% CI) |
Specificity (%) (95% CI) |
Sensitivity (%) (95% CI) |
Specificity (%) (95% CI) |
|
| ≥3200 | 41.4 (35.8–50.8) | 99 (100–100) | 53.4 (47–60.6) | 99 (100–100) |
| 1600 | 55.7 (48.1–67.2) | 99 (96.9–100) | 77.3 (68.2–87.6) | 99.5 (95–100) |
| 800 | 78.6 (71.6–85.2) | 89.9 (62.5–100) | 87.5 (84.7–90.1) | 70.5 (38.8–100) |
| <400 | 88.9 (85.4–91.1) | 59.2 (31.2–100) | 91.4 (88.8–92.7) | 58.6 (26–100) |
Abbreviation: IFA, immunofluorescence assay.