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. 2020 May 11;12(5):442. doi: 10.3390/pharmaceutics12050442

Figure 4.

Figure 4

Internalization of EVs. EVs are internalized into cells through macropinocytosis, clatherin or calveolin-mediated endocytosis, lipid raft-mediated endocytosis, fusion, and phagocytosis. EVs deliver their cargo (proteins, RNAs, and DNAs), which is released into the cytoplasm or ER. EV, extracellular vesicle; ER, endoplasmic reticulum. Figure created with BioRender.