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. 2020 May 23;12(5):476. doi: 10.3390/pharmaceutics12050476

Figure 2.

Figure 2

Contour plot of the effect of (A) X1 = A: curcumin concentration (mg/mL) versus X2 = B: surfactant concentration (% w/v), (B) X1 = A: curcumin concentration (mg/mL) versus X2 = C: S/A ratio (V/V) (C) X1 = B: surfactant concentration (% w/v) X2 = C: versus S/A ratio (V/V), on the NC size using poloxamer 188. 3D surface of the effect of (D) X1 = A: curcumin concentration (mg/mL) versus X2 = B: surfactant concentration (% w/v), (E) X1 = A: curcumin concentration (mg/mL) versus X2 = C: S/A ratio (V/V) (F) X1 = B: surfactant concentration (% w/v) versus X2 = C: S/A ratio (V/V), on the NC size using PVP. 3D surface of the effect of (G) X1 = A: curcumin conc. (mg/mL) versus X2 = B: surfactant concentration (% w/v), (H) X1 = A: curcumin conc. (mg/mL) versus X2 = C: S/A ratio (V/V) (I) X1 = B: surfactant concentration (% w/v) versus X2 = C: S/A ratio (V/V), on the NC size using Polysorbate 80.