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. 2020 Apr 28;12(5):404. doi: 10.3390/pharmaceutics12050404

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Histological assessment of corneal sections after treatment. Representative images of the central corneal section were depicted on day 7 following chemical cauterization. The development of fibrovascular proliferation was observed (red arrows). Groups: (A) normal, (B) PBS, (C) EGCG, (D) GEH, (E) GEH-RGD. Abbreviation: PBS: Phosphate buffer saline, EGCG: epigallocatechin-3 gallate, HA: hyaluronic acid, RGD: arginine-glycine-aspartic acid, GE: Gelatin/EGCG self-assembling nanoparticles (NPs), GEH: GE NPs with HA surface coating, GEH-RGD: GE NPs with HA-RGD surface decoration.