Figure 6.
Viable M. tuberculosis recovered from Hilar lymph nodes and extra-thoracic tissues. Representative tissue samples collected from spleen (A), kidney (B), liver (C), and tracheobronchial lymph nodes (D) were homogenised and cultured on selective agarose for assessment of M. tuberculosis bacterial load in extrapulmonary and extra-thoracic tissues. Individual points represent log10CFU/g tissue recovered from each animal with the group median indicated by horizontal bar. Animals in which disease met humane end-point criteria are indicated with red data points. Significant differences between groups determined by Mann–Whitney U-test are shown.