Table 2.
Occurrence of microscopic changes associated with M. tuberculosis infection.
Group | Vaccine and Route |
Animal ID | Pulmonary | Extra-Pulmonary Tissues | Lymph Nodes | |||||
---|---|---|---|---|---|---|---|---|---|---|
Lung Lesion Type (1–6) |
Bronchus Associated Lymphoid Tissue Involvement | Multi-Nucleated Giant Cells | Spleen | Liver | Kidney | Lung Associated | Peripheral | |||
(n of 7 Lung Lobes) | Present (+) or Absent (-) | |||||||||
Group A | BCG Aerosol | U12 | 1, 2, 4, 5 | 0 | 5 | - | - | - | + | - |
U26 | 1, 2, 4, 5, 6 | 0 | 6 | + | + | - | + | - | ||
U41 | 1, 2, 4, 5, 6 | 0 | 7 | + | + | + | + | - | ||
U46 | 1, 4, 5, 6 | 1 | 7 | - | - | - | + | - | ||
U58 | 1, 2, 4, 5 | 3 | 7 | - | - | - | + | - | ||
U66 | 2, 3, 4, 5, 6 | 0 | 6 | - | + | + | + | - | ||
Group B | BCG ID |
U18 | 1, 2, 4, 5, 6 | 1 | 5 | - | + | + | + | + |
U28 | 1, 2, 3, 4, 5, 6 | 3 | 7 | + | + | + | + | - | ||
U31 | 1, 2, 4, 5, 6 | 1 | 6 | + | + | + | + | + | ||
U56 | 1, 4, 5, 6 | 0 | 3 | + | + | - | + | + | ||
U72 | 1, 4, 5, 6 | 0 | 4 | + | + | - | + | - | ||
Group C | No vaccine |
U15 | 1, 4, 5, 6 | 0 | 5 | + | + | + | + | + |
U22 | 1, 2, 4, 5, 6 | 0 | 6 | + | + | + | + | + | ||
U36 | 1, 2, 4, 5, 6 | 1 | 6 | + | + | + | + | - | ||
U49 | 1, 2, 3, 4, 5, 6 | 0 | 7 | + | + | + | + | - | ||
U57 | 4, 5, 6 | 0 | 4 | - | - | + | + | + | ||
U60 | 1, 2, 4, 5, 6 | 0 | 5 | + | + | + | + | + | ||
U73 | 1, 4, 5, 6 | 0 | 7 | + | + | + | + | + |