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. 2020 Apr 25;12(5):394. doi: 10.3390/pharmaceutics12050394

Table 2.

Occurrence of microscopic changes associated with M. tuberculosis infection.

Group Vaccine
and Route
Animal ID Pulmonary Extra-Pulmonary Tissues Lymph Nodes
Lung Lesion Type
(1–6)
Bronchus Associated Lymphoid Tissue Involvement Multi-Nucleated Giant Cells Spleen Liver Kidney Lung Associated Peripheral
(n of 7 Lung Lobes) Present (+) or Absent (-)
Group A BCG Aerosol U12 1, 2, 4, 5 0 5 - - - + -
U26 1, 2, 4, 5, 6 0 6 + + - + -
U41 1, 2, 4, 5, 6 0 7 + + + + -
U46 1, 4, 5, 6 1 7 - - - + -
U58 1, 2, 4, 5 3 7 - - - + -
U66 2, 3, 4, 5, 6 0 6 - + + + -
Group B BCG
ID
U18 1, 2, 4, 5, 6 1 5 - + + + +
U28 1, 2, 3, 4, 5, 6 3 7 + + + + -
U31 1, 2, 4, 5, 6 1 6 + + + + +
U56 1, 4, 5, 6 0 3 + + - + +
U72 1, 4, 5, 6 0 4 + + - + -
Group C No
vaccine
U15 1, 4, 5, 6 0 5 + + + + +
U22 1, 2, 4, 5, 6 0 6 + + + + +
U36 1, 2, 4, 5, 6 1 6 + + + + -
U49 1, 2, 3, 4, 5, 6 0 7 + + + + -
U57 4, 5, 6 0 4 - - + + +
U60 1, 2, 4, 5, 6 0 5 + + + + +
U73 1, 4, 5, 6 0 7 + + + + +