Skip to main content
. 2020 May 18;12(5):1459. doi: 10.3390/nu12051459

Figure 2.

Figure 2

Oral administration of sesamol prevents obesity in high-fat diet (HFD)-induced obese mice. (A) Body weights of vehicle control- or sesamol-treated mice. Eight-week-old male C57BL/6J mice were fed with normal diets (ND) or high-fat diets (HFD, 60% fat) and orally administrated with the vehicle control or sesamol (100 mg/kg and 200 mg/kg per day) up to 12 weeks (n = 5 per group). Energy expenditure (EE) was measured at 3 weeks of treatments. (B) Differences in epididymal white adipose tissue (eWAT), inguinal white adipose tissue (iWAT), liver, and interscapular brown adipose tissue (iBAT) weights in control- and sesamol-treated groups. (C) Representative images of eWAT from control- or sesamol-treated mice. Scale bar, 10 mm. (D) Representative hematoxylin and eosin (H and E) staining for sections of liver and eWAT from HFD-fed mice. Scale bar, 0.1 mm. Data represent mean ± s.e.m. Statistically significant differences between the control- and sesamol-treated mice were determined by Student’s t-test (* p < 0.05; ** p < 0.005).