Table A1.

Regression coefficient (RC) of the models and their statistical parameters on the responses (Xi: coded values of independent variables (i = 1: pH; i = 2: temperature, i = 3: agitation speed; i = 4: fermentation time) and their interactions.

Source	DF	Orange Pigment Yield		Red Pigment Yield		Dry Biomass Weight
		RC	p Value *	RC	p Value *	RC	p Value *
Model	14	1.74	<0.0001	1.92	<0.0001	6.80	<0.0001
X1	1	0.35	<0.0001	0.28	<0.0001	0.77	<0.0001
X2	1	−0.11	0.0009	−0.090	0.0058	−0.77	<0.0001
X3	1	0.27	<0.0001	0.20	<0.0001	1.24	<0.0001
X4	1	−0.029	0.2767	−0.015	0.5901	−0.17	0.1837
X12	1	−0.11	0.0245	−0.087	0.0927	−0.24	0.2788
X13	1	−0.19	0.0009	−0.17	0.0031	−0.02	0.9224
X14	1	0.11	0.0245	0.075	0.1394	−0.61	0.0117
X23	1	0.41	<0.0001	0.31	<0.0001	1.18	<0.0001
X24	1	0.000	1.000	−0.019	0.7011	0.55	0.0210
X34	1	0.10	0.0418	0.071	0.1615	0.17	0.4359
X12	1	−0.42	<0.0001	−0.33	<0.0001	−1.02	<0.0001
X22	1	−0.68	<0.0001	−0.54	<0.0001	−2.31	<0.0001
X32	1	−0.35	<0.0001	−0.31	<0.0001	−1.35	<0.0001
X42	1	−0.38	<0.0001	−0.32	<0.0001	−0.97	<0.0001
R2		0.9853		0.9734		0.9714
AdjR2		0.9706		0.9468		0.9429
PreR2		0.9172		0.8469		0.8445
CV%		9.12		7.41		9.41
Adeq. Pre.		28.30		21.04		22.71

R²: Determination coefficient; AdjR²: adjusted R^2; PreR²: predicted R²; CV%: coefficient of variation; and Adeq. Pre.: predicted adequacy. p < 0.01 highly significant; 0.01 < p < 0.05 significant; and p > 0.05 not significant.