Table 4.
Physicochemical properties of liquid lipids used in the preparation of NLCs.
| Liquid Lipid Type | General Class | Chemical Name | C-Length | M.wt Average (g/mol) | Viscosity (20 °C) (mPa·s) | Hydrophilic-Lipophilic Balance (HLB) |
|---|---|---|---|---|---|---|
| Oleic acid | Fatty acids | Octadec-9-enoic acid | C18 | 282.5 | 40 | 1 |
| Labrasol® | Polyglycolyzed glycerides | Caprylo caproyl Polyoxyl-8 glycerides | C8–C10 | 400 | 80–110 | 12 |
| Capryol® 90 | PG fatty acid esters | Propylene glycol monocaprylate (type II) | C8 | 202.29 | 20 | 5 |
| Miglyol® 840 | PG fatty acid esters | Propylene glycol diester of saturated vegetable fatty acids | C8-C10 | 709 | 9–12 | <10 |