Table 5.

Studies assessing different species using pyrosequencing.

Author and Year of Publication	Assessed Situation	Actinomyces spp.	Campylobacter spp.	Fusobacterium spp.	Gemella spp.	Parvimonas spp.	Porphyromonas spp.	Prevotella spp.	Rothia spp.	Staphylococcus spp.	Streptococcus spp.	Tannerella spp.	Treponema spp.	Veillonella spp.	n
Studies comparing healthy sites with peri-implantitis-affected sites
Da Silva et al., 2014 [55]	PI	+	+	+	+	+	+	-	+	-	-	-	-	+	10
	HI	+	+	+	+	+	+	-	+	-	-	-	-	+	10
Tsigarida et al., 2015 [90]	PI	+	+	+	+	+	+	+	+	+	+	+	+	+	40
	HI	+	+	+	+	+	+	+	+	+	+	+	+	+	20
Zheng et al., 2015 [97]	PI	+	x	+	+	x	x	x	x	x	x	x	+	+	6
	HI	+	x	-	+	x	x	x	x	x	x	x	-	+	10
Studies comparing healthy sites with peri-implantitis-affected and periodontitis-affected sites
Dabdoub et al., 2013 [56]	PI	+	+	+	+	-	+	+	+	+	+	+	+	+	20
	HI	+	+	+	+	-	+	+	+	+	+	+	+	+	12
	PAR	+	+	+	+	-	+	+	+	+	+	+	+	+	17
Kumar et al., 2012 [66]	PI	+	+	+	+	+	+	+	+	+	+	-	+	+	10
	HI	+	+	-	+	+	+	+	+	-	+	-	+	-	10
	PER	+	+	+	+	+	+	+	+	+	+	-	+	+	10
Study comparing peri-implantitis sites with periodontitis sites
Maruyama et al., 2014 [69]	PI	+	-	+	-	+	+	+	+	+	+	+	+	+	20
	PER	+	-	+	-	+	+	+	+	+	+	+	+	+	20
Shiba et al., 2016 [87]	PI	+	+	-	-	+	+	+	+	-	+	+	+	-	12
	PER	+	+	-	+	+	+	+	+	-	+	+	+	+	12

PI—implants with peri-implantitis, HI—healthy implants, PER—teeth with periodontitis, spp. —species, + positive detection, - no detection, x not assessed, n—number of samples assessed for the respective study.