Figure 5.

TMT-based quantification of the aortic proteomes. (a) Workflow for TMT protein profiling of aorta in this study. (b) Protein identification results. 4,956 proteins (unique peptides ≥ 1) were identified from 28,957 unique peptides. (c) The number of up- and downregulated proteins in each comparison group. (d) Venn diagram of the distribution and overlaps of differentially expressed proteins among the two comparison groups. (e) Hierarchical clustering of 199 common differentially expressed proteins. WT: wild-type; BBR: berberine.