Table 2.

BMI adjusted and multivariate adjusted cox proportional hazard models for incident hypertension risk based on time varying distributions of egg consumption and cholesterol consumption, with follow-up from 1993–2014.

Weekly Egg Intake
	<1.0	1.0–1.9	2–2.9	3.0–3.9	4.0–6.9	≥ 7.0	P for trend
Cases	2512	3144	2428	1959	2342	761
Person years	179,297	218,736	165,256	129,013	145,639	49,387
M0	ref	1.06 [1.01: 1.12]	1.10 [1.04: 1.17]	1.15 [1.09: 1.23]	1.22 [1.15: 1.29]	1.13 [1.05: 1.23]	<0.0005
M1	ref	1.03 [0.98: 1.09]	1.06 [1.00: 1.12]	1.10 [1.03: 1.16]	1.13 [1.07: 1.20]	1.04 [0.96: 1.12]	<0.0005
M2	ref	1.03 [0.98: 1.09]	1.06 [1.01: 1.13]	1.09 [1.03: 1.16]	1.11 [1.05: 1.17]	1.04 [0.96: 1.13]	<0.0005
M3	ref	1.01 [0.95: 1.06]	1.04 [0.98: 1.10]	1.07 [1.01: 1.13]	1.11 [1.05: 1.18]	1.00 [0.92: 1.09]	0.001
M4	ref	1.03 [0.98: 1.09]	1.07 [1.01: 1.13]	1.10 [1.04: 1.17]	1.14 [1.06: 1.18]	1.04 [0.96: 1.14]	<0.0005
Quintiles of Cholesterol Intake (mg/day)
	≤270	271–336	337–401	402–487	≥ 488	P for trend
Cases	2488	2614	2689	2607	2709
Person years	176,926	177,661	177,362	177,884	175,639
M0	ref	1.15 [1.09: 1.22]	1.19 [1.13: 1.26]	1.24 [1.18: 1.31]	1.29 [1.22: 1.36]	<0.0005
M1	ref	1.12 [0.98: 1.10]	1.15 [1.02: 1.14]	1.17 [0.97: 1.09]	1.18 [0.99: 1.11]	<0.0005
M2	ref	1.13 [1.07: 1.20]	1.17 [1.10: 1.24]	1.20 [1.13: 1.28]	1.22 [1.14: 1.30]	<0.0005
M3*	ref	1.04 [0.98: 1.10]	1.06 [0.99: 1.12]	1.08 [1.02: 1.16]	1.10 [1.03: 1.18]	0.007
M4	ref	1.13 [1.07: 1.20]	1.17 [1.02: 1.14]	1.20 [1.13: 1.28]	1.22 [1.14: 1.30]	<0.0005

M0 non adjusted, with age as timeline; M1 adjusted for BMI; M2 adjusted for total physical activity, total calories, smoking, family history of CVD, education level, menopausal status, use of MHT, dyslipidaemia, and diabetes; M3 adjusted for M2 + intake of alcohol, unprocessed meat, processed meat, vegetables, fruits, shellfish, fish, salt, potassium and saturated fats; M3* adjusted for M2 + intake of vegetables, fruits, salt, potassium and saturated fats; M4 adjusted for M2 + Mediterranean diet score.