Table 2.
Interaction between genetic risk score and lifestyle factors on clinical and biochemical parameters.
| Outcome Measures | Physical Activity Levels | Protein% | Fat% | Carbohydrates% | Saturated Fatty Acids g/d * | Polyunsaturated Fatty Acids g/d * | Monounsaturated Fatty Acids g/d * |
|---|---|---|---|---|---|---|---|
| Body Mass Index | 0.89 | 0.94 | 0.16 | 0.20 | - | - | - |
| Waist Circumference | 0.45 | 0.70 | 0.54 | 0.47 | - | - | - |
| 25(OH)D ** | 0.90 | 0.69 | 0.32 | 0.047 | - | - | - |
| Fasting Plasma Glucose | 0.12 | 0.90 | 0.16 | 0.09 | - | - | - |
| Glycated Hemoglobin | 0.13 | 0.52 | 0.44 | 0.32 | - | - | - |
| Fasting Plasma Insulin | 0.84 | 0.41 | 0.14 | 0.76 | |||
| Systolic Blood Pressure | 0.72 | 0.19 | 0.96 | 0.62 | - | - | - |
| Diastolic Blood Pressure | 0.93 | 0.93 | 0.22 | 0.54 | - | - | - |
| Total Cholesterol | 0.80 | 0.40 | 0.47 | 0.55 | - | - | - |
| Low density lipoprotein Cholesterol | 0.90 | 0.12 | 0.032 | 0.028 | 0.21 | 0.28 | 0.27 |
| High density lipoprotein cholesterol | 0.68 | 0.55 | 0.72 | 0.80 | - | - | - |
| Fasting serum triglycerides | 0.87 | 0.11 | 0.26 | 0.11 | - | - | - |
p value for interactions obtained by general linear univariate analysis. All interactions were adjusted for age, gender, type 2 diabetes and BMI (except BMI) * Adjusted for log-total energy intake; ** Adjusted for month of sample collection.