Figure 5.

Functional classification of MAB upregulated proteins by ≥1.5-fold. Enriched proteins of (A) anaerobic and biofilm conditions; (B) aerobic condition during exposure to AMK or LNZ; (C) anaerobic condition during exposure to AMK or LNZ; and (D) biofilm condition during exposure to AMK or LNZ. The analysis was done by finding MAB protein homologs in M. tuberculosis H37Rv strain and using the functional categorization available on TubercuList webserver of Institute Pasteur. MAB proteins that did not show any homology were classified based on predicted or known function for conserved domain/motif search at NCBI (National Center for Biotechnology Information) and the Pfam database through the Sanger Institute. Histograms show number of proteins belonging to each functional category.