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Treatment with EZH2 inhibitors has no effect on body weight in STAM NASH mice. (A) Effect of EZH2 inhibitors (UNC1999, EPZ-6438) and obeticholic acid on body weight. (B) Effect of EZH2 inhibitors on the liver, kidney, and white adipose tissue relative weight. Relative organ weight was measured as the weight of the organ divided by the body weight. Data are shown as mean ± standard deviation (n = 5). Abbreviations: WAT, white adipose tissue.
