Table 1.
Characteristic of study population at baseline (T0) stratified by nutritional status according to GLIM criteria.
| GLIM Criteria | ||||
|---|---|---|---|---|
| All (n = 41) | Malnourished (n = 7; 17%) | Non-Malnourished (n = 34; 83%) | p Value | |
| Gender | ||||
| Female (number, %) | 30 (73) | 4 (57) | 26 (77) | 0.361 |
| Male (number, %) | 11 (27) | 3 (43) | 8 (23) | |
| Age (y) | 82.4 ± 6.6 | 81.1 ± 8.0 | 82.6 ± 6.3 | 0.660 |
| Height (m) | 1.61 ± 0.1 | 1.67 ± 0.1 | 1.60 ± 0.1 | 0.036 |
| Actual body weight (kg) | 73.9 ± 16.8 | 66.5 ± 13.1 | 75.4 ± 17.2 | 0.150 |
| BMI (kg/m2) | 28.4 ± 6.4 | 23.5 ± 3.8 | 29.4 ± 6.4 | 0.006 |
| Weight loss in 6 months (kg) | 2.2 ± 3.1 | 5.8 ± 3.0 | 1.4 ± 2.6 | 0.006 |
| CRP (mg/dl) | 2.5 ± 5.5 | 2.5 ± 1.9 | 2.5 ± 6.0 | 0.969 |
| Total MNA-SF, Median (IQR) | 8 (10–12) | 9 (7–9) | 11 (9–12) | 0.010 |
| Barthel Index on admission, Median (IQR) | 55 (40–67) | 35 (35–45) | 60 (40–70) | 0.005 |
| Walking, Median (IQR) | 5 (5–10) | 5 (5–5) | 10 (5–10) | 0.025 |
| Frail Simple scale score, Median (IQR) | 3 (2–3) | 3 (3–4) | 3 (2–3) | 0.006 |
| SARC-F scores, Median (IQR) | 6 (4–7) | 5 (3–8) | 6 (4–7) | 0.747 |
| CCI score, Median (IQR) | 2 (1–3) | 1 (1–3) | 2 (1–2) | 0.959 |
| Mobility Status | ||||
| Mobile (number, %) | 19 (46) | 0 (0) | 19 (56) | 0.010 |
| Immobile (number, %) | 22 (54) | 7 (100) | 15 (44) | |
| Length of hospital stay | 16 (14–18) | 16 (14–17) | 16 (14–18) | 0.577 |
| Time between MRI scans | 14 (11–14) | 14 (11–14) | 13 (11–14) | 0.667 |
GLIM, Global Leadership Initiative on Malnutrition; CRP, C-reactive protein; MNA-SF, Mini Nutritional Assessment Short Form (normal nutritional status 12–14 points, at risk of malnutrition 8–11 points and malnourished 0–7 points); Frail Simple scale (not frail with score 0, pre-frail with scores of 1–2 and frail with 3–5); SARC-F scores (high risk of sarcopenia with score ≥4); CCI, Charlson Comorbidity Index; MRI, Magnetic Resonance Imaging. Values are given as mean ± SD, number (%) or median (IQR, interquartile range).