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. 2020 May 19;12(5):463. doi: 10.3390/pharmaceutics12050463

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Photographs illustrating the effect of (a) the negative control (normal saline solution), (b) the positive control (1% SLS solution), (c) chili extract solution, (d) blank SLN, (e) chili extract-loaded SLN, (f) blank NLC, and (g) chili extract-loaded NLC in the hen’s egg test chorioallantoic membrane (HET-CAM) assay before applying the samples (upper panels) and at the end of the experiment (lower panels). Abbreviations: SLS, sodium lauryl sulphate; SLN, solid lipid nanoparticles; NLC, nanostructured lipid carriers; H, vascular hemorrhage; L, vascular lysis.